Description

1H-Isoindole-1,3(2H)-Dione, 4-Chloro-2-Phenyl- is a high-purity, synthetically valuable organic intermediate characterized by its distinct isoindole-1,3-dione (phthalimide) core structure. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the development of novel compounds with specific functionalities. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals. Its defined structure and purity are critical for ensuring reproducibility and efficacy in downstream applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the chlorophenyl-substituted phthalimide structure can impart unique biological activity.
• Material Science: Acts as a monomer or functional additive in the synthesis of specialized polymers, such as polyimides, which require high thermal and chemical stability.
• Organic Synthesis Building Block: Employed in various name reactions and coupling chemistries to introduce the 4-chloro-2-phenylphthalimide moiety into more complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal-organic frameworks (MOFs) or asymmetric catalysis due to its potential chelating properties.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 4-Chloro-2-Phenyl-
CAS No.	42899-83-2
Molecular Formula	C14H8ClNO2
Molecular Weight	257.67 g/mol
Synonyms	4-Chloro-2-phenyl-1H-isoindole-1,3(2H)-dione; 4-Chloro-2-phenylphthalimide; 2-Phenyl-4-chlorophthalimide; N-Phenyl-4-chlorophthalimide; 4-Chloro-N-phenylphthalimide; 4-Chloro-2-phenyl-1,3-dihydro-2H-isoindole-1,3-dione; 4-Chloro-2-phenylisoindoline-1,3-dione
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione, 4-Chloro-2-Phenyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.