Description

2-Chloro-1-(1H-Indol-3-Yl)-2-Phenyl-Ethanone is a versatile and high-value indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both indole and phenylketone moieties, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole-based alkaloids and potential drug candidates targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing novel plant growth regulators or pesticides with specific biological activity.
• Material Science: Used in the research and development of advanced organic electronic materials and functional dyes.
• Academic & R&D: Fundamental reagent in methodological organic synthesis for studying novel reaction mechanisms and constructing molecular libraries.
• Chemical Biology: Probe or linker molecule for studying protein interactions and biochemical pathways.

Basic Information

Item	Detail
Product Name	2-Chloro-1-(1H-Indol-3-Yl)-2-Phenyl-Ethanone
CAS No.	42883-45-4
Molecular Formula	C₁₆H₁₂ClNO
Molecular Weight	269.73 g/mol
Synonyms	3-(2-Chloro-2-oxo-1-phenylethyl)-1H-indole; 2-Chloro-1-(1H-indol-3-yl)-2-phenylethanone; 2-Chloro-2-phenyl-1-(1H-indol-3-yl)ethanone; α-Chloro-α-phenyl-3-indolyl ketone; 3-(α-Chlorobenzoyl)indole; 42883-45-4; Indole-3-(α-chlorobenzoyl)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-(1H-Indol-3-Yl)-2-Phenyl-Ethanone is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.