Description

(Cyanomethyl)Trimethylphosphanium Iodide is a versatile organophosphonium salt with significant utility in advanced organic synthesis. Its primary value lies in its role as a key reagent for the synthesis of cyanomethyl ylides and as a precursor for functionalized phosphonium compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce cyanomethyl or phosphonium functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing phosphonium or cyanoethyl groups.
• Wittig Reaction Precursor: Used to generate stabilized ylides for the Wittig olefination, enabling the synthesis of alkenes with adjacent nitrile functionality.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, insecticides, and plant growth regulators.
• Ligand and Catalyst Development: Acts as a precursor for phosphine ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Utilized in the creation of ionic liquids, functional polymers, and other advanced materials with tailored properties.
• Chemical Biology Probes: Applied in the synthesis of labeled compounds and probes for studying biological mechanisms.

Basic Information

Item	Detail
Product Name	(Cyanomethyl)Trimethylphosphanium Iodide
CAS No.	42843-99-2
Molecular Formula	C5H11INP
Molecular Weight	267.03 g/mol
Synonyms	Trimethyl(cyanomethyl)phosphonium iodide; (Cyanomethyl)trimethylphosphonium iodide; (Cyanomethyl)-trimethylphosphanium iodide; Phosphonium, (cyanomethyl)trimethyl-, iodide (1:1); Acetonitrile, (iodotrimethylphosphoranylidene)-; (Iodotrimethyl-λ5-phosphanylidene)acetonitrile
EINECS	Contact for details

Quality Control

Our (Cyanomethyl)Trimethylphosphanium Iodide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.