Description

Diethyl(4-Aminophenyl)Phosphonate is a versatile organophosphorus compound featuring both an amino group and a phosphonate ester moiety. This bifunctional structure makes it a valuable key intermediate in the synthesis of more complex molecules, particularly in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where the aminophenyl phosphonate structure imparts specific biological activity.
• Ligand and Catalyst Precursor: The amino and phosphonate groups allow it to act as a precursor for chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Flame Retardant Synthon: Incorporated into polymers and resins as a starting material for developing phosphorus-containing flame retardant additives.
• Material Science Research: Employed in the creation of specialty monomers for advanced polymers, coatings, and adhesives with enhanced properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and inhibitors for studying enzymatic processes.

Basic Information

Product Name	Diethyl(4-Aminophenyl)Phosphonate
CAS No.	42822-57-1
Molecular Formula	C10H16NO3P
Molecular Weight	229.21 g/mol
Synonyms	Diethyl P-(4-Aminophenyl)phosphonate; 4-Aminophenylphosphonic Acid Diethyl Ester; Phosphonic Acid, P-(4-Aminophenyl)-, Diethyl Ester; Diethyl 4-Aminobenzene-1-phosphonate; (4-Aminophenyl)phosphonic Acid Diethyl Ester; Diethyl (p-Aminophenyl)phosphonate; p-Aminophenylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl(4-Aminophenyl)Phosphonate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.