Description

3-Amino-1-Hydroxyindolin-2-One Hydrochloride is a high-purity, pharmaceutically relevant indoline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Utilized in the construction of complex heterocyclic compounds and indole-based molecular libraries for drug discovery.
• Research & Development: Essential for medicinal chemistry research, process development, and scale-up studies in academic and industrial laboratories.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in manufacturing.

Basic Information

Product Name	3-Amino-1-Hydroxyindolin-2-One Hydrochloride
CAS No.	42794-39-8
Molecular Formula	C8H9N2O2·HCl
Molecular Weight	200.63 g/mol (Free base: 164.17 g/mol)
Synonyms	1-Hydroxy-3-aminoindolin-2-one hydrochloride; 3-Amino-1-hydroxy-2-indolinone hydrochloride; 2-Indolinone, 3-amino-1-hydroxy-, hydrochloride; 3-Amino-1-hydroxyindolin-2-one HCl; 1-Hydroxy-3-amino-2-indolinone hydrochloride; 3-Amino-1-hydroxy-2-oxindole hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-1-Hydroxyindolin-2-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.