Description

L-2-Bromophenylalanine is a non-natural, chiral amino acid derivative featuring a bromine substituent on the phenyl ring. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the introduction of both amino acid functionality and a halogen handle for further derivatization. It is primarily utilized by pharmaceutical research organizations, agrochemical developers, and specialty chemical manufacturers for applications in drug discovery, peptide mimetics, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitors and receptor ligands.
• Peptidomimetics & Constrained Peptides: Used to incorporate modified phenylalanine residues into peptide chains to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the design of chiral herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Used as a substrate analog in enzyme inhibition studies and mechanistic investigations.
• Material Science: A potential monomer for the synthesis of specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	L-2-Bromophenylalanine
CAS No.	42538-40-9
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	(S)-2-Amino-3-(2-bromophenyl)propanoic acid; L-2-Bromo-phenylalanine; (S)-2-Bromophenylalanine; H-2-Br-Phe-OH; Boc-2-Br-Phe-OH (protected form); Fmoc-2-Br-Phe-OH (protected form); 2-Bromo-L-phenylalanine; 2-Bromophenylalanine, L- isomer
EINECS	Contact for details

Quality Control

Our L-2-Bromophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.