Description

2-(5-Chlorothiophen-2-Yl)Acetonitrile is a versatile and high-purity organic building block, specifically a functionalized thiophene derivative. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and advanced material sectors who require reliable, high-quality intermediates for heterocyclic chemistry and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing the thiophene moiety for various therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the chlorothiophene structure imparts specific biological activity.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, such as conductive polymers and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex dyes and functional pigments.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic institutions engaged in novel heterocyclic compound discovery.

Basic Information

Product Name	2-(5-Chlorothiophen-2-Yl)Acetonitrile
CAS No.	42520-90-1
Molecular Formula	C6H4ClNS
Molecular Weight	157.62 g/mol
Synonyms	5-Chloro-2-thiopheneacetonitrile; (5-Chloro-2-thienyl)acetonitrile; 2-(5-Chloro-2-thienyl)acetonitrile; 5-Chlorothiophene-2-acetonitrile; 2-Thiopheneacetonitrile, 5-chloro-; 5-Chloro-2-thiophenecarbonitrile; α-Cyano-5-chlorothiophene
EINECS	Contact for details

Quality Control

Our 2-(5-Chlorothiophen-2-Yl)Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.