Description

Phenylphosphonic Acid Bis(Trimethylsilyl) Ester is a high-purity organosilicon-protected phosphonate reagent, essential for synthetic chemistry where moisture-sensitive intermediates are required. Its primary value lies in its role as a versatile silylating agent and protected phosphonic acid synthon, enabling precise and efficient bond formation. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing phosphonate or phosphate ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require phosphonate-based active ingredients.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized phosphonate ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce phosphonate groups into polymer backbones, enhancing properties like flame retardancy, adhesion, or metal chelation.
• Surface Functionalization: Utilized to modify material surfaces (e.g., silica, metals) with organic phosphonate layers for improved compatibility or specific reactivity.
• Protecting Group Strategy: The bis(trimethylsilyl) group effectively protects the phosphonic acid moiety during multi-step synthetic sequences, which is later cleaved under mild conditions.

Basic Information

Product Name	Phenylphosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	42449-24-1
Molecular Formula	C12H23O3PSi2
Molecular Weight	302.46 g/mol
Synonyms	Bis(trimethylsilyl) Phenylphosphonate; Phenylphosphonic Acid Bis(trimethylsilyl) Ester; Phenylphosphonic Acid, Bis(trimethylsilyl) Ester; Phenylphosphonic Acid Bis(TMS) Ester; (Trimethylsilyl) Phenylphosphonate; Phosphonic acid, P-, bis(trimethylsilyl) ester; TMS-Phenylphosphonate
EINECS	Contact for details

Quality Control

Every batch of Phenylphosphonic Acid Bis(Trimethylsilyl) Ester is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation, ensuring supply chain integrity for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.