Description

Succinic Anhydride-1 4-14C CAS NO 42415-11-2 is a carbon-14 labeled derivative of succinic anhydride, a versatile cyclic dicarboxylic acid anhydride. This isotopically labeled compound is essential for advanced research and development, enabling precise metabolic and pharmacokinetic studies through tracer techniques. It is primarily required by pharmaceutical R&D laboratories, agrochemical scientists, and academic researchers working in the fields of organic synthesis, biochemistry, and materials science.

Application

• Tracer Studies in Pharmaceutical Research: Used as a radiolabeled intermediate to track the metabolic fate, absorption, and distribution of new drug candidates and their metabolites.
• Biochemical Pathway Analysis: Employed in investigating the Krebs cycle (TCA cycle) and other succinate-involved metabolic pathways in biological systems.
• Polymer Science Research: Serves as a labeled monomer or cross-linking agent in the development and degradation studies of biodegradable aliphatic polyesters.
• Agrochemical Metabolism Studies: Utilized to study the environmental fate, biodegradation, and metabolic pathways of agrochemicals and plant growth regulators.
• Organic Synthesis Intermediate: Acts as a building block for the synthesis of more complex 14C-labeled compounds, including pharmaceuticals, dyes, and resins.
• Material Science & Surface Modification: Used in research to create labeled surface coatings or to study the mechanism of succinoylation reactions on various substrates.

Basic Information

Product Name	Succinic Anhydride-1 4-14C
CAS No.	42415-11-2
Molecular Formula	C414CH4O3
Molecular Weight	~102.06 g/mol (with 14C)
Synonyms	1,4-14C-Succinic Anhydride; [1,4-14C]Succinic Anhydride; Butanedioic Anhydride-1,4-14C; 2,5-Diketotetrahydrofuran-1,4-14C; Dihydro-2,5-furandione-1,4-14C; Succinic Acid Anhydride-1,4-14C; NSC 8416-1,4-14C
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled succinic anhydride is produced and analyzed under strict quality protocols to ensure high chemical and radiochemical purity, specific activity, and stability. Our quality system emphasizes traceability and reproducibility for research integrity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as radiochemical purity (by HPLC), chemical purity, specific activity, and solvent content. We adhere to GLP (Good Laboratory Practice) principles in our analytical procedures.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., argon or nitrogen) in a desiccator to maintain stability and prevent hydrolysis. For long-term storage, keep at temperatures between 2°C and 8°C. Follow all applicable local and international regulations for the storage of radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98.0%
Radiochemical Purity (HPLC)	≥ 97.0%
Specific Activity	Customizable (mCi/mmol)
Solvent (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.