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B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonane CAS NO 42371-63-1
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CAS No.:42371-63-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonane is a highly valuable chiral organoborane reagent, specifically a pinene-derived 9-BBN derivative. Its primary value lies in its exceptional stereoselectivity and stability, making it a superior choice for asymmetric hydroboration reactions in complex organic synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity, reliable chiral building blocks.
Application
- Asymmetric Hydroboration: Key reagent for the stereoselective synthesis of chiral alcohols from prochiral alkenes, a critical step in producing active pharmaceutical ingredients (APIs) and natural products.
- Pharmaceutical Intermediate Synthesis: Used in the production of enantiomerically pure intermediates for drugs targeting central nervous system disorders, cardiovascular diseases, and anti-infectives.
- Agrochemical Research: Enables the creation of chiral active ingredients for herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
- Fine Chemical Manufacturing: Serves as a cornerstone in the synthesis of specialty chemicals, flavors, fragrances, and advanced polymer precursors where chirality dictates function.
- Academic & Process Chemistry: A staple in research laboratories and scale-up facilities for developing novel synthetic routes and optimizing catalytic processes.
Basic Information
| Item | Details |
|---|---|
| Product Name | B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonane |
| CAS No. | 42371-63-1 |
| Molecular Formula | C₁₉H₃₃B |
| Molecular Weight | 272.27 g/mol |
| Synonyms | (-)-B-Isopinocampheyl-9-borabicyclo[3.3.1]nonane; (-)-Ipc₂BH; (1R)-(-)-B-Isopinocampheyl-9-BBN; Isopinocampheyl-9-BBN; 9-Borabicyclo[3.3.1]nonane, B-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)-, (1R)-; (-)-Diisopinocampheylborane (related precursor); Chiral 9-BBN reagent; Ipc-BBN |
| EINECS | Contact for details |
Quality Control
Every batch of our B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonane is manufactured and tested under strict quality management systems to ensure high chiral purity and chemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and key impurity profiles. Our quality commitment aligns with the standards required for cGMP and ISO 9001 environments, ensuring reliability for your most critical synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C to maintain stability and purity. This material is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or ambient temperature will compromise its reactivity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or solution |
| Identification (IR) | Conforms to structure |
| Assay (NMR/Titration) | ≥ 95.0% |
| Enantiomeric Excess (ee) | ≥ 98.0% (by chiral GC/HPLC) |
| Solvent (if supplied as solution) | Specified (e.g., Tetrahydrofuran, Hexanes) |
| Concentration (if solution) | 0.5 M, 1.0 M, or as requested |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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