Description

4,4'-Dimethyl-D6-Diphenyl is a deuterated isotopologue of 4,4'-dimethylbiphenyl, where six hydrogen atoms are replaced by the stable isotope deuterium. This compound is a critical internal standard and analytical tracer in quantitative mass spectrometry, enabling precise measurement and method validation. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity isotopic labeling for metabolic studies, pharmacokinetics, and degradation pathway analysis.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical methods for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolic Pathway Tracing: Employed in pharmaceutical and agrochemical research to elucidate metabolic and environmental degradation pathways using isotope dilution techniques.
• Polymer & Materials Science Research: Serves as a deuterated monomer or model compound in NMR spectroscopy for studying polymer dynamics, morphology, and synthesis mechanisms.
• Environmental Analysis: Acts as a surrogate or internal standard in the GC-MS or LC-MS analysis of biphenyl derivatives and related persistent organic pollutants.
• Isotope Labeling Studies: Provides a stable, non-radioactive label for mechanistic studies in organic chemistry and catalysis.
• Quality Control & Method Development: Critical for developing and validating sensitive analytical methods in regulatory-compliant laboratories.

Basic Information

Product Name	4,4'-Dimethyl-D6-Diphenyl
CAS No.	42052-87-9
Molecular Formula	C14D6H10
Molecular Weight	190.29 g/mol
Synonyms	4,4'-Dimethylbiphenyl-d6; D6-4,4'-Dimethylbiphenyl; Biphenyl-4,4'-diyl-d6-dimethane; p,p'-Dimethylbiphenyl-d6; 1,1'-Biphenyl, 4,4'-dimethyl-, d6-; Deuterated 4,4'-Dimethylbiphenyl; [D6]-4,4'-Dimethylbiphenyl; 4,4'-Dideuteriomethylbiphenyl
EINECS	Contact for details

Quality Control

Our 4,4'-Dimethyl-D6-Diphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ²H, ¹³C) for isotopic enrichment and structural confirmation, and HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing isotopic purity (atom % D), chemical purity, and all relevant analytical data are provided to ensure compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by ²H NMR)
Chemical Purity (GC)	Contact for details
Residual Solvent (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.