Description

6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester is a key heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its tetrahydroisoquinoline core, a privileged scaffold found in numerous biologically active compounds, making it indispensable for pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of alkaloids, receptor ligands, and potential therapeutic agents targeting the central nervous system.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the tetrahydroisoquinoline moiety with defined stereochemistry for drug discovery programs.
• Agrochemical Research: Employed in the development of novel active ingredients, leveraging its complex heterocyclic structure.
• Chemical Synthesis Reagent: Acts as a versatile starting material for the preparation of more elaborate nitrogen-containing heterocycles in academic and industrial laboratories.
• Process Chemistry: Used in route scouting and optimization for the scalable production of target molecules containing the isoquinoline framework.

Basic Information

Item	Details
Product Name	6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester
CAS No.	41993-68-4
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	Ethyl 6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylate; 1-Carbethoxy-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-1-carboxylic acid ethyl ester; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolinecarboxylic Acid Ethyl Ester; Ethyl 1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.