Description

4-(Chloromethyl)-4-Hydroxy-2-Phenyl-4,5-Dihydro-1,3-Thiazol-3-Ium Chloride is a versatile and reactive heterocyclic organic salt, serving as a critical building block and intermediate in advanced chemical synthesis. Its unique structure, featuring both a chloromethyl group and a thiazolium core, makes it valuable for constructing complex molecules and functional materials. This compound is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel thiazole-based drug candidates, including potential antimicrobials and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Ligand and Catalyst Development: Used to prepare functionalized thiazolium salts, which can act as N-heterocyclic carbene (NHC) precursors or ligands in organometallic catalysis.
• Material Science Research: Intermediate for synthesizing ionic liquids or functional polymers with specific electronic or chemical properties.
• Chemical Biology Probes: Serves as a starting material for creating bioconjugation reagents or probes targeting biological thiols.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	4-(Chloromethyl)-4-Hydroxy-2-Phenyl-4,5-Dihydro-1,3-Thiazol-3-Ium Chloride
CAS No.	41981-14-0
Molecular Formula	C10H11Cl2NO2S
Molecular Weight	280.17 g/mol
Synonyms	4-(Chloromethyl)-4-hydroxy-2-phenyl-4,5-dihydrothiazol-3-ium chloride; 2-Phenyl-4-(chloromethyl)-4-hydroxy-4,5-dihydro-1,3-thiazol-3-ium chloride; 4,5-Dihydro-4-hydroxy-2-phenyl-4-(chloromethyl)thiazol-3-ium chloride; 3H-1,3-Thiazol-3-ium, 4,5-dihydro-4-hydroxy-2-phenyl-4-(chloromethyl)-, chloride; Thiazolium salt intermediate; 41981-14-0
EINECS	Contact for details

Quality Control

Our production of 4-(Chloromethyl)-4-Hydroxy-2-Phenyl-4,5-Dihydro-1,3-Thiazol-3-Ium Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.