Description

5-Nitro-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a versatile and high-value organic intermediate with the CAS registry number 41959-45-9. This compound is a critical building block in the synthesis of complex molecules, prized for its unique nitro-substituted tetrahydroisoquinoline scaffold. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex nitrogen-containing heterocycles.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and herbicides.
• Material Science: Investigated for the preparation of specialty polymers and advanced organic materials.
• Academic & R&D: Utilized in universities and contract research organizations (CROs) for methodological studies and discovery chemistry.

Basic Information

Product Name	5-Nitro-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	41959-45-9
Molecular Formula	C9H10N2O2·HCl
Molecular Weight	214.65 g/mol
Synonyms	5-Nitro-1,2,3,4-tetrahydroisoquinoline HCl; 5-Nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-nitroisoquinoline hydrochloride; 5-Nitro-1,2,3,4-tetrahydro-isoquinoline monohydrochloride; 5-Nitro-THIQ HCl; 5-Nitro-1,2,3,4-tetrahydroisoquinoline HCl salt
EINECS	Contact for details

Quality Control

Every batch of 5-Nitro-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.