Description

[(1-Bromocyclopropyl)Bromomethyl]Benzene is a specialized bifunctional brominated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both a reactive benzyl bromide and a strained cyclopropyl bromide moiety, enabling sequential and site-selective functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular scaffolds, including potential active pharmaceutical ingredients (APIs) and novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing cyclopropane rings or requiring specific spatial orientation.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the cyclopropyl group can impart unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing sophisticated chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Building Block: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials requiring rigid, three-dimensional aromatic units.
• Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) due to its two distinct bromine handles.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, exploring new reaction pathways involving strained rings and halogenated aromatics.

Basic Information

Item	Details
Product Name	[(1-Bromocyclopropyl)Bromomethyl]Benzene
CAS No.	41893-70-3
Molecular Formula	C10H10Br2
Molecular Weight	289.99 g/mol
Synonyms	α-Bromo-1-bromocyclopropylbenzene; (1-Bromocyclopropyl)(bromomethyl)benzene; Benzene, [(1-bromocyclopropyl)bromomethyl]-; 1-Bromo-1-(bromomethyl)cyclopropylbenzene; (Bromomethyl)(1-bromocyclopropyl)benzene; 1-(Bromomethyl)-1-bromocyclopropylbenzene; α-(1-Bromocyclopropyl)benzyl bromide
EINECS	Contact for details

Quality Control

Our [(1-Bromocyclopropyl)Bromomethyl]Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.