Description

(2-Bromo-1-Cyclobuten-1-Yl)Benzene is a specialized brominated cyclobutene derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a bromine atom on a strained cyclobutene ring fused to a benzene moiety, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions, cycloadditions, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring strained ring systems or specific halogenated motifs for biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bromocyclobutene unit can impart unique properties to the final molecule.
• Material Science: Serves as a monomer or building block for creating advanced polymers and functional materials with specific optical or electronic properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent leaving group in palladium-catalyzed reactions like Suzuki, Negishi, or Stille couplings for carbon-carbon bond formation.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis, leveraging the steric and electronic properties of the cyclobutene ring.
• Academic & Industrial R&D: A crucial reagent for methodological development and exploring new chemical spaces in both university and corporate research laboratories.

Basic Information

Item	Details
Product Name	(2-Bromo-1-Cyclobuten-1-Yl)Benzene
CAS No.	41893-67-8
Molecular Formula	C10H9Br
Molecular Weight	209.08 g/mol
Synonyms	1-Bromo-2-phenylcyclobut-1-ene; 2-Bromo-1-phenyl-1-cyclobutene; 2-Bromo-1-phenylcyclobut-1-ene; (2-Bromocyclobuten-1-yl)benzene; Benzene, (2-bromo-1-cyclobuten-1-yl)-; 1-Cyclobutene-1-ylbenzene, 2-bromo-
EINECS	Contact for details

Quality Control

Our (2-Bromo-1-Cyclobuten-1-Yl)Benzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and process chemistry. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.