Description

7-[3-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Propyl]Theophyline is a specialized xanthine derivative with a unique molecular structure that combines theophylline with a catecholamine-like side chain. This compound is valued for its potential as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel bronchodilators and cardiovascular agents. It serves the critical needs of pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of novel adenosine receptor antagonists and bronchodilatory agents.
• Medicinal Chemistry Research: Key scaffold for structure-activity relationship (SAR) studies targeting respiratory and cardiovascular diseases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Used in studies investigating phosphodiesterase (PDE) inhibition and related cellular signaling pathways.
• Fine Chemical Synthesis: Intermediate for the production of more complex, target-specific molecules in custom synthesis projects.

Basic Information

Product Name	7-[3-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Propyl]Theophyline
CAS No.	41760-38-7
Molecular Formula	C₁₈H₂₃N₅O₅
Molecular Weight	389.41 g/mol
Synonyms	7-[3-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethyl-2,6-purinedione; 7-(3-{[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino}propyl)theophylline; Theophylline, 7-[3-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-; 1,3-Dimethyl-7-[3-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]xanthine; Droxifylline (related compound); Adentri (related compound); A-80226 (research code)
EINECS	Contact for details

Quality Control

Our 7-[3-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Propyl]Theophyline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.