Description

2-Bromo-4-Nitrothiazole is a versatile halogenated nitroheterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents on the thiazole ring, makes it a valuable electrophilic building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. Its reactivity profile allows for selective functionalization, enabling the synthesis of targeted compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Research: Employed as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle in the design of chemical probes and affinity labels for studying biological systems.
• Dye & Pigment Intermediate: Serves in the synthesis of complex heterocyclic dyes and colorants for specialized applications.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to the reactivity of the bromine substituent.

Basic Information

Item	Details
Product Name	2-Bromo-4-Nitrothiazole
CAS No.	41731-79-7
Molecular Formula	C3HBrN2O2S
Molecular Weight	208.99 g/mol
Synonyms	2-Bromo-4-nitro-1,3-thiazole; 4-Nitro-2-bromothiazole; Thiazole, 2-bromo-4-nitro-; 2-Brom-4-nitrothiazol; 2-Bromo-4-nitro-thiazole; Bromonitrothiazole
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-4-Nitrothiazole adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We are committed to meeting the specific requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.