Description

2-Bromothiazole-5-Sulfonic Acid is a high-value brominated heterocyclic sulfonic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electrophilic bromine atom and a strongly acidic sulfonic acid group, makes it an indispensable reagent for introducing functionalized thiazole motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the thiazole ring contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Functional Material Development: Employed in the research and production of dyes, pigments, and electronic chemicals due to its sulfonic acid functionality.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular targets.
• Academic & Industrial Research: Used in exploratory chemistry for constructing complex heterocyclic libraries for high-throughput screening.

Basic Information

Product Name	2-Bromothiazole-5-Sulfonic Acid
CAS No.	41731-70-8
Molecular Formula	C3H2BrNO3S2
Molecular Weight	244.08 g/mol
Synonyms	5-Bromothiazole-2-sulfonic Acid; 2-Bromo-1,3-thiazole-5-sulfonic Acid; Thiazole, 2-bromo-5-sulfo-; 2-Bromothiazole-5-sulfonic acid (ACI); 5-Bromo-2-thiazolesulfonic Acid; 2-Bromo-5-thiazolesulfonic Acid; 2-Bromothiazole-5-sulphonic Acid; 5-Bromothiazole-2-sulphonic Acid
EINECS	Contact for details

Quality Control

Our 2-Bromothiazole-5-Sulfonic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after initial use to prevent degradation from atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.