Description

2-Chloroinosine 3’,4’,6’-Triacetate is a key nucleoside derivative and a protected intermediate of significant synthetic utility. This compound is valued for its role in the synthesis of modified nucleosides and nucleotides, which are crucial building blocks in medicinal chemistry and biochemical research. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel therapeutic agents and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a building block for modified oligonucleotides and nucleotide prodrugs.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and drug discovery programs.
• Agrochemical Development: Potential intermediate in the synthesis of novel plant growth regulators or pesticides.
• Academic Research: Employed in organic synthesis laboratories for studying nucleoside chemistry and developing new synthetic methodologies.
• Diagnostic Reagent Synthesis: Can be used in the preparation of labeled nucleosides for diagnostic assays.

Basic Information

Product Name	2-Chloroinosine 3’,4’,6’-Triacetate
CAS No.	41623-86-3
Molecular Formula	C₁₆H₁₇ClN₄O₈
Molecular Weight	428.78 g/mol
Synonyms	2-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine; 2-Chloroinosine Triacetate; 2-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)hypoxanthine; 2-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purin-6(1H)-one; 2-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-6-oxopurine; 2-Chloroadenosine Triacetate Derivative (common misnomer); 2-Cl-Ino(Ac)₃
EINECS	Contact for details

Quality Control

Our 2-Chloroinosine 3’,4’,6’-Triacetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.