Description

n-Hydroxyphthalimide Triflate, 99+%, Ele CAS NO 41580-58-9 is a high-purity, specialized reagent primarily used as a powerful triflating agent in organic synthesis. This compound is critical for introducing the highly reactive trifluoromethanesulfonate (triflate) group, enabling a wide range of advanced chemical transformations. It is an essential building block for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the preparation of active pharmaceutical ingredients (APIs), particularly in nucleoside and nucleotide chemistry.
• Catalyst and Ligand Preparation: Used to synthesize sophisticated organometallic catalysts and ligands for asymmetric catalysis.
• Polymer Chemistry: Employed in the creation of functional monomers and specialty polymers with tailored properties.
• Agrochemical Research: Serves as a precursor for novel herbicides, fungicides, and plant growth regulators.
• Material Science: Facilitates the development of advanced organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions like Suzuki, Stille, and Negishi couplings.

Basic Information

Product Name	n-Hydroxyphthalimide Triflate, 99+%, Ele CAS NO 41580-58-9
CAS No.	41580-58-9
Molecular Formula	C9H4F3NO5S
Molecular Weight	295.19 g/mol
Synonyms	N-Hydroxyphthalimide Trifluoromethanesulfonate; 1-Hydroxy-1H-isoindole-1,3(2H)-dione Triflate; N-Hydroxyphthalimide Triflate; NHPI Triflate; Phthalimide N-Oxy Triflate; Trifluoromethanesulfonic Acid 1-Hydroxy-1,3-dihydro-2H-isoindol-2-ylidene Ester; N-Hydroxyphthalimide Trifluoromethanesulfonic Acid Ester; 41580-58-9
EINECS	Contact for details

Quality Control

Our n-Hydroxyphthalimide Triflate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and FTIR to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.