Description

2-(4-Phenyl-1,3-thiazol-2-yl)acetonitrile is a versatile organic building block featuring a thiazole core linked to a phenyl group and a reactive nitrile functionality. This compound matters for its role as a key intermediate in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including liquid crystals, organic semiconductors, and fluorescent dyes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP for clinical trial materials.

Basic Information

Product Name	2-(4-Phenyl-1,3-thiazol-2-yl)acetonitrile
CAS No.	41381-89-9
Molecular Formula	C11H8N2S
Molecular Weight	200.26 g/mol
Synonyms	2-(4-Phenylthiazol-2-yl)acetonitrile; 2-(4-Phenyl-1,3-thiazol-2-yl)ethanenitrile; 4-Phenyl-2-thiazoleacetonitrile; (4-Phenyl-1,3-thiazol-2-yl)acetonitrile; 2-(4-Phenylthiazol-2-yl)ethanenitrile; 2-(4-Phenyl-2-thiazolyl)acetonitrile; Acetonitrile, 2-(4-phenyl-2-thiazolyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Phenyl-1,3-thiazol-2-yl)acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.