Description

Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a key chiral intermediate for the development of complex pharmaceutical molecules, particularly in the synthesis of alkaloids and other bioactive compounds. It is primarily required by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, cardiovascular drugs, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of tetrahydroisoquinoline-based alkaloids and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and development of novel drug candidates targeting neurological and cardiovascular diseases.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective reactions to construct complex molecular architectures.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Academic & Industrial R&D: Utilized in research laboratories for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate
CAS No.	41234-43-9
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	Ethyl 1,2,3,4-tetrahydro-3-isoquinolinecarboxylate; Ethyl 3,4-dihydro-1(2H)-isoquinolinecarboxylate; 3-Carbethoxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ethyl ester; ETIC; TEQ-CA-OEt
EINECS	Contact for details

Quality Control

Our Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.