Description

D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and asymmetric synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential drug candidates, including enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex, enantiomerically pure molecules in organic and medicinal chemistry.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and conformationally constrained scaffolds for biological evaluation.
• Agrochemical Development: Employed as an intermediate in the synthesis of novel, biologically active compounds for crop protection.
• Chemical Biology Probes: Utilized in the creation of specialized probes and ligands for studying biological pathways and target engagement.
• Academic & Industrial R&D: A critical reagent for method development and discovery chemistry in both university laboratories and corporate R&D facilities.

Basic Information

Product Name	D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	41220-48-8
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid hydrochloride; D-Tic-OH·HCl; (R)-Tic-OH·HCl; (3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid hydrochloride; (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; D-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; (R)-TIC-OH hydrochloride; D-Tetrahydroisoquinoline-3-carboxylic acid HCl
EINECS	Contact for details

Quality Control

Our D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.