Description

6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinolinecarboxylic Acid is a key heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized isoquinoline core, which serves as a versatile precursor for the development of complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new chemical entities, particularly for central nervous system (CNS) and cardiovascular targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex alkaloids and bioactive isoquinoline derivatives.
• Medicinal Chemistry Research: Used as a scaffold for designing and synthesizing novel compounds for biological screening against various disease targets.
• Chemical Synthesis Building Block: Employed in heterocyclic chemistry to construct more elaborate molecular architectures through reactions at the carboxylic acid and tetrahydroisoquinoline functionalities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in universities and research institutes for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinolinecarboxylic Acid
CAS No.	41143-95-7
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolinecarboxylic acid; 6,7-Dimethoxy-3,4-dihydro-1-isoquinolinecarboxylic acid; 1-Carboxy-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; THIQ-1-COOH derivative
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.