Description

14-Hydroxymorphine-6-One is a key pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is valued for its high purity and structural specificity, making it essential for analytical and synthetic applications. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of controlled substance standards.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related opioid compounds in research and quality control laboratories.
• Metabolite Studies: Serves as a critical metabolite or degradation product standard in pharmacokinetic and toxicological research.
• Forensic Analysis: Employed as a certified reference material (CRM) for the accurate identification and quantification in forensic toxicology.
• Chemical Synthesis: Acts as a specialized intermediate or starting material in the synthesis of novel pharmaceutical candidates for research purposes.
• Method Development & Validation: Essential for developing and validating analytical methods such as HPLC, GC-MS, and LC-MS/MS in regulatory and compliance settings.
• Impurity Profiling: Used to identify and control related substance impurities in the manufacture of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	14-Hydroxymorphine-6-One
CAS No.	41135-98-2
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	14-Hydroxymorphinone; 14-Hydroxymorphine-6-one; 14-Hydroxy-7,8-didehydromorphinone; 14-Hydroxycodeinone derivative; 14-Hydroxymorphin-6-one; 14-Hydroxy-6-oxomorphine; 14-Hydroxymorphine ketone
EINECS	Contact for details

Quality Control

Our 14-Hydroxymorphine-6-One is produced and handled under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.