Description

Enprofylline is a high-purity xanthine derivative and a potent, selective phosphodiesterase (PDE) inhibitor. This compound is of significant interest in pharmaceutical research and development due to its distinct pharmacological profile compared to other methylxanthines. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for respiratory and inflammatory conditions.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a selective tool compound in pharmacological studies to investigate PDE enzyme inhibition and its downstream cellular effects.
• Respiratory Drug Development: A subject of research for potential applications in asthma, chronic obstructive pulmonary disease (COPD), and other bronchoconstrictive disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Preclinical Studies: Utilized in animal models to study pharmacokinetics, pharmacodynamics, and efficacy for potential new drug candidates.

Basic Information

Product Name	Enprofylline
CAS No.	41078-02-8
Molecular Formula	C10H14N4O2
Molecular Weight	222.25 g/mol
Synonyms	3-Propylxanthine; 3-Propyl-1H-purine-2,6-dione; ENPRO; 1H-Purine-2,6-dione, 3-propyl-; BAY o 2404; BRL 30892; 3-n-Propylxanthine; 3-Propyl-3,7-dihydro-1H-purine-2,6-dione
EINECS	255-207-5

Quality Control

Our Enprofylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all test results against our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.