Description

2-Methyl-4-o-Tolylbut-3-Yn-2-Ol is a specialized tertiary acetylenic alcohol that serves as a valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an alkyne and an aromatic o-tolyl group, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted phenylacetylene scaffold.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and plant growth regulators that leverage its specific aromatic and alkyne functionalities.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored thermal or mechanical properties.
• Organic Synthesis: A versatile building block for Sonogashira coupling and other metal-catalyzed cross-coupling reactions to create complex molecular architectures.
• Ligand Synthesis: Potential precursor for creating novel chiral or bidentate ligands used in asymmetric catalysis and coordination chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-Methyl-4-o-Tolylbut-3-Yn-2-Ol
CAS No.	40888-14-0
Molecular Formula	C₁₂H₁₄O
Molecular Weight	174.24 g/mol
Synonyms	2-Methyl-4-(2-methylphenyl)but-3-yn-2-ol; 4-(2-Methylphenyl)-2-methyl-3-butyn-2-ol; 2-Methyl-4-(o-tolyl)-3-butyn-2-ol; o-Tolyl Methyl Butynol; 3-Butyn-2-ol, 2-methyl-4-(2-methylphenyl)-; 2-Methyl-4-(2-methylphenyl)-2-hydroxy-3-butyne
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-o-Tolylbut-3-Yn-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.