Description

5-Chloro-3H-Imidazo[4,5-B]Pyridine-2-Thiol is a high-purity heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. This specialized intermediate is valued for its unique fused-ring structure, which incorporates both imidazole and pyridine motifs along with reactive chloro and thiol functional groups. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functional additive in the research of conductive polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research due to its reactive thiol group.
• Organic Synthesis: A versatile scaffold for constructing complex nitrogen-containing heterocycles in academic and industrial R&D settings.

Basic Information

Product Name	5-Chloro-3H-Imidazo[4,5-B]Pyridine-2-Thiol
CAS No.	40851-97-6
Molecular Formula	C6H4ClN3S
Molecular Weight	185.63 g/mol
Synonyms	5-Chloro-2-mercapto-3H-imidazo[4,5-b]pyridine; 5-Chloro-2-thioxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine; 5-Chloro-1H-imidazo[4,5-b]pyridine-2-thiol; 5-Chloro-2-thioxo-1,2-dihydro-3H-imidazo[4,5-b]pyridine; 5-Chloro-3H-imidazo[4,5-b]pyridine-2-thione; 40851-97-6; 5-Chloro-2-mercaptoimidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3H-Imidazo[4,5-B]Pyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.