Description

6,7-Dihydroxytetrahydroisoquinoline is a high-purity, versatile tetrahydroisoquinoline derivative with significant synthetic utility. This compound serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis, particularly for the construction of complex alkaloid frameworks. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical industries, where its unique structure enables the creation of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of isoquinoline-based alkaloids and potential active pharmaceutical ingredients (APIs).
• Chiral Building Block: Utilized in asymmetric synthesis for constructing complex molecules with defined stereochemistry.
• Neurological Research: Serves as a core structure in the development of compounds for studying neurological pathways and receptors.
• Agrochemical Synthesis: Intermediate for developing novel crop protection agents and herbicides.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and complex organic materials.
• Academic & R&D: Fundamental research compound in medicinal chemistry and organic synthesis laboratories.

Basic Information

Product Name	6,7-Dihydroxytetrahydroisoquinoline
CAS No.	40704-74-3
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-isoquinolinediol; 6,7-Dihydroxy-THIQ; 6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (salt form); THIQ-6,7-diol; NSC 403169; 6,7-Dihydroxy-THIQ base
EINECS	Contact for details

Quality Control

Our 6,7-Dihydroxytetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.