Description

Methyl 2-Hydroxy-2-Methyl-D3-Propionate--D3 is a deuterium-labeled isotopologue of methyl 2-hydroxy-2-methylpropionate, a key building block in organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity, stable isotope-labeled materials for advanced analytical and synthetic applications. It is primarily utilized in the pharmaceutical, agrochemical, and academic research sectors for applications such as metabolic studies, reaction mechanism elucidation, and the synthesis of labeled target molecules.

Application

• Pharmaceutical Research & Development: As a deuterated intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs) for pharmacokinetic, metabolic, and tracer studies.
• Analytical Chemistry Standards: Serves as an internal standard or reference material in quantitative mass spectrometry (MS), NMR spectroscopy, and other analytical techniques to ensure accuracy and precision.
• Mechanistic Studies: Used to investigate chemical reaction pathways and mechanisms in organic and organometallic chemistry due to the kinetic isotope effect (KIE) of deuterium.
• Agrochemical Development: Employed in the synthesis of deuterium-labeled pesticides or herbicides for environmental fate and metabolism studies.
• Material Science: Potential use in the development of specialty polymers or advanced materials where isotopic labeling is required to study structure-property relationships.
• Academic & Industrial Research: A versatile reagent for synthetic chemists in universities and corporate R&D labs exploring novel synthetic methodologies involving labeled compounds.

Basic Information

Product Name	Methyl 2-Hydroxy-2-Methyl-D3-Propionate--D3
CAS No.	40662-44-0
Molecular Formula	C5H5D3O3
Molecular Weight	119.15 g/mol
Synonyms	Methyl 2-Hydroxy-2-methylpropionate-d3; Methyl 2-Hydroxyisobutyrate-d3; 2-Hydroxy-2-methylpropionic Acid Methyl Ester-d3; Methyl α-Hydroxyisobutyrate-d3; Methyl 2-Methyl-2-hydroxypropionate-d3; Methyl 2-Hydroxy-2-(trideuteriomethyl)propanoate; (2-Hydroxy-2-methylpropanoic Acid)-d3 Methyl Ester; Deuterated Methyl 2-Hydroxyisobutyrate
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR (¹H, ²H, ¹³C) and GC-MS or LC-MS. Certificates of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity, and identity are provided with every shipment. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC or HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by ²H NMR or MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.