Description

(S)-(+)-1-Chloro-2-Methylbutane CAS NO 40560-29-0 is a high-purity chiral building block essential for asymmetric synthesis. Its value lies in its role as a versatile alkylating agent and a key intermediate for introducing the (S)-2-methylbutyl moiety into complex molecules. This compound is critically needed by research institutions and pharmaceutical companies developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure drugs and bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands for asymmetric catalysis.
• Flavor and Fragrance Industry: Intermediate for creating specific, high-value chiral aroma compounds.
• Material Science Research: Building block for novel chiral polymers and liquid crystals with specialized optical properties.
• Organic Synthesis: Versatile reagent for nucleophilic substitution reactions to construct complex carbon chains with defined stereochemistry.

Basic Information

Product Name	(S)-(+)-1-Chloro-2-Methylbutane
CAS No.	40560-29-0
Molecular Formula	C5H11Cl
Molecular Weight	106.59 g/mol
Synonyms	(S)-1-Chloro-2-methylbutane; (S)-(+)-2-Methylbutyl chloride; (S)-sec-Butylmethyl chloride; (S)-Chloromethylbutane; (S)-1-Chloro-2-methylbutane; (S)-2-Methyl-1-chlorobutane; (+)-(S)-1-Chloro-2-methylbutane; sec-Butylmethyl chloride (S-enantiomer)
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Chloro-2-Methylbutane is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.408 - 1.412
Specific Rotation ([α]20D)	+5.0° to +7.0° (c=1 in chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.