Description

1 α-Acetyldinormethadol is a synthetic opioid derivative and a key chemical intermediate in advanced pharmaceutical research and development. Its primary value lies in its role as a controlled precursor for the synthesis of specialized medicinal compounds and for analytical reference standards. This compound is essential for pharmaceutical manufacturers, forensic laboratories, and research institutions engaged in neuropharmacology, analgesic development, and substance analysis. We supply this material with a focus on high purity, batch-to-batch consistency, and full regulatory documentation to support critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized opioid-based active pharmaceutical ingredients (APIs) and novel therapeutic agents.
• Reference Standard: Used as a certified analytical standard in forensic, clinical, and pharmaceutical testing laboratories for method validation and substance identification.
• Biochemical Research: Employed in academic and industrial research to study opioid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Controlled Substance Analysis: Essential for the development and calibration of analytical equipment (e.g., GC-MS, HPLC) used in drug testing and law enforcement.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the production of related pharmaceutical compounds under controlled conditions.

Basic Information

Product Name	1 α-Acetyldinormethadol
CAS No.	40488-01-5
Molecular Formula	C22H29NO2
Molecular Weight	339.47 g/mol
Synonyms	1α-Acetyldinormethadol; 1-α-Acetylmethadol; 1α-Acetylmethadol; Noracymethadol; NIH 10420; 6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate; α-1-Acetyldinormethadol
EINECS	Contact for details

Quality Control

Every batch of 1 α-Acetyldinormethadol is manufactured and tested under strict quality management systems to ensure the highest standards of purity and identity. Our products undergo rigorous analytical testing, including chromatographic purity assays and spectroscopic identification, to meet the stringent requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent degradation. Keep the container securely sealed and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.