Description

4-Bromo-5-Ethyl-Thiophene-2-Carboxylic Acid is a high-purity, functionalized thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both bromo and carboxylic acid functionalities into complex target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the production of conductive polymers, organic semiconductors, and specialty coatings.
• Chemical Research: Employed as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Stille) and for further derivatization into esters, amides, or other functional groups.
• Ligand and Catalyst Development: Useful for constructing complex ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.

Basic Information

Product Name	4-Bromo-5-Ethyl-Thiophene-2-Carboxylic Acid
CAS No.	40477-61-0
Molecular Formula	C7H7BrO2S
Molecular Weight	235.10 g/mol
Synonyms	5-Ethyl-4-bromothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-bromo-5-ethyl-; 4-Bromo-5-ethyl-2-thiophenecarboxylic acid; 4-Bromo-5-ethylthiophene-2-carboxylic acid; 40477-61-0; 5-Ethyl-4-bromo-2-thiophenecarboxylic acid; 4-Bromo-5-ethylthiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Ethyl-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.