Description

2-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid hydrochloride is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its fused indole and pyridine ring system, which provides a versatile scaffold for constructing pharmacologically active molecules. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Process Development: Serves as a reference standard and a critical material in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Academic Research: Employed in synthetic organic chemistry studies to develop new methodologies for constructing complex heterocyclic frameworks.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's discovery and development pipelines.

Basic Information

Product Name	2-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid hydrochloride
CAS No.	40431-45-6
Molecular Formula	C14H17ClN2O2
Molecular Weight	280.75 g/mol
Synonyms	8-Carboxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride; 2-Methyl-1,2,3,4-tetrahydro-8-carboline-8-carboxylic acid hydrochloride; 8-Carboxy-2-methyl-β-carboline hydrochloride; 40431-45-6; Tetrahydro-β-carboline-8-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for research and development purposes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.