Description

Butanedioic Acid Bis(Trimethylsilyl) Ester is a high-purity silylating agent and synthetic intermediate of significant importance in advanced organic synthesis. Its primary value lies in its ability to protect reactive functional groups, particularly carboxylic acids, facilitating complex multi-step reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and reliable reagents for process development and active ingredient synthesis. CAS No. 40309-57-7.

Application

• Derivatization Agent in Analytical Chemistry: Used to prepare volatile derivatives of carboxylic acids for Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS) analysis.
• Pharmaceutical Intermediate: Serves as a key protecting group reagent in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the production of advanced pesticides, herbicides, and plant growth regulators where sensitive functional groups require protection.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialized silicones and other functional polymers.
• Organic Synthesis Research: A versatile tool in academic and industrial R&D labs for constructing complex molecular architectures, including natural products.
• Production of Silicon-Containing Compounds: Used as a precursor or reagent for introducing trimethylsilyl groups into target molecules.

Basic Information

Product Name	Butanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	40309-57-7
Molecular Formula	C10H24O4Si2
Molecular Weight	264.47 g/mol
Synonyms	Bis(trimethylsilyl) Succinate; Succinic Acid Bis(trimethylsilyl) Ester; 1,4-Bis(trimethylsilyloxy)-1,4-dioxobutane; Tetramethyl Succinate Derivative; TMS Succinate; Succinic Acid, bis(trimethylsilyl) ester; Bis-O-(trimethylsilyl)succinate; Succinic Acid Di(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our Butanedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports applications requiring reliable and reproducible performance in sensitive synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.