Description

2-(1H-Indol-3-Ylmethylene)-5,5-Dimethyl-1,3-Cyclohexanedione is a versatile chemical intermediate characterized by its unique molecular structure combining indole and cyclohexanedione moieties. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for creating novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural complexity for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and natural product analogs.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	2-(1H-Indol-3-Ylmethylene)-5,5-Dimethyl-1,3-Cyclohexanedione
CAS No.	40302-35-0
Molecular Formula	C₁₇H₁₇NO₂
Molecular Weight	267.32 g/mol
Synonyms	5,5-Dimethyl-2-(1H-indol-3-ylmethylene)-1,3-cyclohexanedione; 2-[(1H-Indol-3-yl)methylene]-5,5-dimethyl-1,3-cyclohexanedione; 3-(5,5-Dimethyl-2,6-dioxocyclohexylidene)indole; Dimedone Indole Derivative; Indole-3-carboxaldehyde Dimedone Adduct; 40302-35-0; (E)-2-(1H-Indol-3-ylmethylene)-5,5-dimethylcyclohexane-1,3-dione
EINECS	Contact for details

Quality Control

Our 2-(1H-Indol-3-Ylmethylene)-5,5-Dimethyl-1,3-Cyclohexanedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.