Description

[[(3β)-5α-Ergosta-7,22-Dien-3-Yl]Oxy]Trimethylsilane is a high-purity sterol derivative, specifically a trimethylsilyl (TMS) ether of a key ergostadiene intermediate. This compound is a critical building block in advanced organic synthesis, valued for its role in protecting reactive hydroxyl groups and facilitating complex molecular transformations. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis laboratories for the production of novel steroidal compounds, vitamin D analogs, and other high-value bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel steroidal drugs and vitamin D derivatives.
• Organic Synthesis Building Block: Used as a protected sterol intermediate for constructing complex molecular architectures in research and development.
• Biochemical Research: Employed in the study of sterol metabolism and the synthesis of labeled compounds for tracer studies.
• Fine Chemical Production: Serves as a precursor in the manufacture of high-purity specialty chemicals for the life sciences industry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	[[(3β)-5α-Ergosta-7,22-Dien-3-Yl]Oxy]Trimethylsilane
CAS No.	40272-63-7
Molecular Formula	C31H54OSi
Molecular Weight	470.85 g/mol
Synonyms	5α-Ergosta-7,22-dien-3β-ol trimethylsilyl ether; Ergosta-7,22-dien-3-ol, (3β,5α)-, trimethylsilyl ether; (3β,5α)-Ergosta-7,22-dien-3-yloxy-trimethylsilane; 5α-Ergosta-7,22-dien-3β-yl TMS ether; TMS ether of 5α-ergosta-7,22-dien-3β-ol; 40272-63-7; Trimethyl((3β,5α)-ergosta-7,22-dien-3-yloxy)silane
EINECS	Contact for details

Quality Control

Our [[(3β)-5α-Ergosta-7,22-Dien-3-Yl]Oxy]Trimethylsilane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. We support cGMP compliance for applications requiring the highest material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.