Description

2-Keto-4-Methyl-3H-Thiazole-5-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of thiazole-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the thiazole moiety for biological activity.
• Fine Chemical Manufacturing: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Biochemical Research: Employed in academic and industrial laboratories for studying enzyme inhibitors and developing new biochemical probes.
• Material Science: Potential intermediate for the development of organic electronic materials and specialty polymers.

Basic Information

Product Name	2-Keto-4-Methyl-3H-Thiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	40235-78-7
Molecular Formula	C7H9NO3S
Molecular Weight	187.22 g/mol
Synonyms	Ethyl 4-Methyl-5-oxo-2,5-dihydro-1,3-thiazole-2-carboxylate; Ethyl 2,4-Dihydro-4-methyl-5-oxo-1,3-thiazole-2-carboxylate; 4-Methyl-5-oxo-2,5-dihydrothiazole-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-4-methyl-5-thiazolone; 2-Ethoxycarbonyl-4-methyl-5-thiazolone; 4-Methylrhodanine-2-carboxylic Acid Ethyl Ester; 2-Keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Keto-4-Methyl-3H-Thiazole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.