Description

3-Iodo-2,5-Dimethylthiophene is a high-purity halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of novel thiophene derivatives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to the electron-rich nature of the thiophene ring.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form complex biaryl systems.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Chemical Research: A valuable reagent in academic and industrial research for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Iodo-2,5-Dimethylthiophene
CAS No.	40197-02-2
Molecular Formula	C6H7IS
Molecular Weight	238.09 g/mol
Synonyms	2,5-Dimethyl-3-iodothiophene; 3-Iodo-2,5-dimethylthiophene; Thiophene, 3-iodo-2,5-dimethyl-; 2,5-Dimethyl-3-thienyl iodide
EINECS	Contact for details

Quality Control

Our 3-Iodo-2,5-Dimethylthiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.