Description

3-Benzyloxy-2,2-dimethoxy-propan-1-ol is a versatile protected glycerol derivative and a valuable chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex molecules. It is particularly relevant for the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, including antiviral agents, cardiovascular drugs, and other bioactive compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific stereochemistry.
• Fine Chemical Production: Serves as a building block for specialty surfactants, polymers, and liquid crystals where controlled molecular architecture is needed.
• Glycidyl Ether Chemistry: Acts as a precursor in the synthesis of various glycidyl ether derivatives used in epoxy resins and other polymer systems.
• Protecting Group Strategy: The benzyloxy and dimethoxy groups provide orthogonal protection for diols and polyols in multi-step synthetic routes.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	3-Benzyloxy-2,2-dimethoxy-propan-1-ol
CAS No.	40166-30-1
Molecular Formula	C₁₂H₁₈O₄
Molecular Weight	226.27 g/mol
Synonyms	1,3-Dihydroxy-2,2-dimethoxypropane benzyl ether; 2,2-Dimethoxy-3-(phenylmethoxy)-1-propanol; 3-(Benzyloxy)-2,2-dimethoxy-1-propanol; Glycerol 1-benzyl ether 2,2-dimethyl acetal; Benzyl 2,2-dimethoxy-3-hydroxypropyl ether; 1-Propanol, 3-(benzyloxy)-2,2-dimethoxy-; 3-O-Benzyl-1,2-O-isopropylidene glycerol (related protected form)
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-2,2-dimethoxy-propan-1-ol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity, identity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from tests such as HPLC assay, chiral purity, and identification by spectroscopic methods. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.