Description

3-Amino-Benzenethiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific thiophene-based motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require the unique properties of the benzothiophene scaffold.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the amino and carboxylic acid groups allow for color tuning and polymer attachment.
• Ligand and Catalyst Development: The functional groups make it a versatile starting point for creating chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Research: A valuable reagent for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific molecular targets.

Basic Information

Product Name	3-Amino-Benzenethiophene-2-Carboxylic Acid
CAS No.	40142-71-0
Molecular Formula	C9H7NO2S
Molecular Weight	193.22 g/mol
Synonyms	2-Carboxy-3-aminobenzo[b]thiophene; 3-Amino-1-benzothiophene-2-carboxylic acid; 3-Aminobenzo[b]thiophene-2-carboxylic Acid; 3-Amino-2-benzothiophenecarboxylic acid; 2-Benzothiophenecarboxylic acid, 3-amino-; 3-Amino-benzo[b]thiophene-2-carboxylic acid; 3-Amino-2-carboxybenzo[b]thiophene
EINECS	Contact for details

Quality Control

Our 3-Amino-Benzenethiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.