Description

2-(4-Chloro-Phenyl)-Thiophene is a versatile heterocyclic aromatic compound featuring a chlorophenyl substituent, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in its role as a fundamental building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene-chlorophenyl core structure.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and organic semiconductors used in OLEDs, solar cells, and field-effect transistors (OFETs).
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and discovery chemistry programs exploring new chemical entities and structure-activity relationships (SAR).
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color fastness and specific light-absorption properties.

Basic Information

Product Name	2-(4-Chloro-Phenyl)-Thiophene
CAS No.	40133-23-1
Molecular Formula	C10H7ClS
Molecular Weight	194.68 g/mol
Synonyms	4-Chlorophenylthiophene; 2-(4-Chlorophenyl)thiophene; 2-(p-Chlorophenyl)thiophene; 1-Chloro-4-(thiophen-2-yl)benzene; Thiophene, 2-(4-chlorophenyl)-; 4-(2-Thienyl)chlorobenzene; p-Chlorophenylthiophene
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Phenyl)-Thiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.