Description

5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid is a high-purity brominated thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a thiophene heterocycle with a brominated phenyl group, enabling precise functionalization in complex chemical pathways. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and liquid crystal materials.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a core component in the synthesis of novel electroluminescent materials for display technologies.

Basic Information

Product Name	5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid
CAS No.	40133-13-9
Molecular Formula	C11H7BrO2S
Molecular Weight	283.14 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(4-bromophenyl)-; 5-(p-Bromophenyl)thiophene-2-carboxylic acid; 4-Bromo-α-thiophen-2-yl-benzenecarboxylic acid; 5-(4-Bromophenyl)-2-thiophenecarboxylic acid; 5-(4-Bromophenyl)thiophene-2-carboxylate; 40133-13-9; 5-(4-Bromophenyl)-2-thiophene carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for fine chemical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.