Description

3-Thiophenecarboxylic Acid, 3-Aminotetrahydro-, 1-Oxide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a functionalized thiophene ring with an amine and an N-oxide group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a building block for conductive polymers and advanced organic electronic materials due to the thiophene moiety.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and enzyme inhibition.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 3-Aminotetrahydro-, 1-Oxide
CAS No.	40057-26-9
Molecular Formula	C5H7NO3S
Molecular Weight	161.18 g/mol
Synonyms	3-Aminotetrahydrothiophene-3-carboxylic acid 1-oxide; Tetrahydro-3-amino-3-thiophenecarboxylic acid 1-oxide; 3-Amino-3-carboxytetrahydrothiophene 1-oxide; 3-Aminotetrahydrothiophene-3-carboxylic acid N-oxide; (3R/S)-3-Aminotetrahydrothiophene-3-carboxylic acid 1-oxide; 3-Thiophenecarboxylic acid, 3-aminohexahydro-, 1-oxide; 3-Carboxy-3-aminotetrahydrothiophene 1-oxide
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarboxylic Acid, 3-Aminotetrahydro-, 1-Oxide is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.