Description

5-(o-Chlorophenyl)-7-Ethyl-1,2-Dihydro-3H-Thieno[2,3-E][1,4]Diazepine-2-Thione is a high-purity, complex heterocyclic compound serving as a critical pharmaceutical intermediate and research chemical. Its unique fused-ring structure containing diazepine and thiophene moieties makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material synthesis sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system (CNS).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in academic and industrial laboratories.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	5-(o-Chlorophenyl)-7-Ethyl-1,2-Dihydro-3H-Thieno[2,3-E][1,4]Diazepine-2-Thione
CAS No.	40054-40-8
Molecular Formula	C15H13ClN2S2
Molecular Weight	320.86 g/mol
Synonyms	7-Ethyl-5-(2-chlorophenyl)-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepine-2-thione; 5-(2-Chlorophenyl)-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepine-2-thione; Thienodiazepine-2-thione derivative; 40054-40-8; 5-(o-Chlorophenyl)-7-ethyl-1,2-dihydro-3H-thieno[2,3-e]-1,4-diazepine-2-thione
EINECS	Contact for details

Quality Control

Our production of 5-(o-Chlorophenyl)-7-Ethyl-1,2-Dihydro-3H-Thieno[2,3-E][1,4]Diazepine-2-Thione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.