Description

6-Hydroxyindole-2-Carboxylic Acid is a versatile heterocyclic building block and key intermediate in organic synthesis. Its unique indole scaffold functionalized with both a phenolic hydroxyl and a carboxylic acid group makes it a valuable precursor for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for applications ranging from drug discovery to specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of indole-based active pharmaceutical ingredients (APIs), including potential serotonin analogs and kinase inhibitors.
• Agrochemical Research: Used in the development of novel plant growth regulators and pesticides that leverage the indole structure.
• Biochemical Research: Serves as a precursor or standard in studies related to tryptophan metabolism and melanin synthesis pathways.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and conductive organic materials.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments due to its chromophoric indole core.
• Chemical Synthesis Building Block: Employed in multi-step organic synthesis for constructing more complex heterocyclic systems and natural product analogs.

Basic Information

Product Name	6-Hydroxyindole-2-Carboxylic Acid
CAS No.	40047-23-2
Molecular Formula	C9H7NO3
Molecular Weight	177.16 g/mol
Synonyms	6-Hydroxy-1H-indole-2-carboxylic acid; 2-Carboxy-6-hydroxyindole; 6-Hydroxyindole-2-carboxylate; 6-HOICA; 6-Hydroxy-2-indolecarboxylic acid; 2-Indolecarboxylic acid, 6-hydroxy-; 6-Hydroxy-2-carboxyindole
EINECS	Contact for details

Quality Control

Our 6-Hydroxyindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay by HPLC, identification by FT-IR, and control of related substances. Our quality commitment ensures reliable performance for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.