Description

Ethyl 4-Nitro-1H-Indole-2-Carboxylate is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized indole scaffold with orthogonal reactive sites, enabling the efficient construction of complex heterocyclic molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various biologically active indole alkaloids and potential drug candidates targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, dyes, and photoresponsive polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and the discovery of new chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty reagents for diagnostic and analytical applications.

Basic Information

Product Name	Ethyl 4-Nitro-1H-Indole-2-Carboxylate
CAS No.	4993-93-5
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	4-Nitro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4-nitroindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 4-nitro-, ethyl ester; 2-Carbethoxy-4-nitroindole; 4-Nitroindole-2-carboxylic Acid Ethyl Ester; Ethyl 4-nitro-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Nitro-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air and light should be avoided. Keep container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.