Description

p-tert-Butyl-Thiophenol (CAS NO 4946-15-0) is a specialized organosulfur compound featuring a bulky tert-butyl group adjacent to a thiol functionality. This structural configuration makes it a valuable intermediate and ligand in advanced chemical synthesis, offering unique steric and electronic properties. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and polymer industries for applications requiring precise molecular control.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring thioether linkages or as a precursor for metal-chelating agents.
• Polymerization Modifier & Chain Transfer Agent: Used to control molecular weight and modify end-group functionality in radical polymerization processes for specialty polymers and resins.
• Ligand in Catalysis: Acts as a ligand for transition metal catalysts in cross-coupling reactions and other organometallic transformations due to its electron-donating and sterically demanding nature.
• Agrochemical Synthesis: Employed in the production of certain herbicides, fungicides, and insecticides where the tert-butyl-thiophenol moiety contributes to biological activity.
• Material Science Research: Used in the development of self-assembled monolayers (SAMs), organic electronic materials, and as a surface modifier for nanoparticles.
• Flavor & Fragrance Ingredient: Functions as a precursor for sulfur-containing aroma chemicals, contributing to savory or roasted notes in complex flavor formulations.

Basic Information

Product Name	p-tert-Butyl-Thiophenol
CAS No.	4946-15-0
Molecular Formula	C10H14S
Molecular Weight	166.28 g/mol
Synonyms	4-tert-Butylbenzenethiol; 4-(tert-Butyl)thiophenol; 4-tert-Butylthiophenol; p-tert-Butylbenzenethiol; 1-tert-Butyl-4-mercaptobenzene; PTBT; Thioguard TBP; 4-(1,1-Dimethylethyl)benzenethiol
EINECS	225-581-6

Quality Control

Our p-tert-Butyl-Thiophenol is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for industrial and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.