Description

Ethyl 2-(1,1-Dioxidotetrahydrothien-3-Yl)-3-Oxobutanoate is a high-purity, specialized organic intermediate featuring a tetrahydrothiophene-1,1-dioxide (sulfolane) moiety and an active β-ketoester functional group. This unique molecular architecture makes it a valuable synthon for constructing complex heterocyclic and pharmaceutical scaffolds, offering versatility in synthetic organic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those containing sulfone or complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive β-ketoester group.
• Organic Synthesis Research: Serves as a versatile precursor for annulation reactions, Michael additions, and the construction of chiral centers in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific sulfone-containing backbones.
• Ligand and Catalyst Development: The molecular structure can be modified to create novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Ethyl 2-(1,1-Dioxidotetrahydrothien-3-Yl)-3-Oxobutanoate
CAS No.	4905-71-9
Molecular Formula	C10H16O5S
Molecular Weight	248.30 g/mol
Synonyms	Ethyl 2-(1,1-Dioxotetrahydro-3-thienyl)-3-oxobutanoate; Ethyl 2-(1,1-Dioxo-tetrahydro-thiophen-3-yl)-3-oxo-butyrate; 3-Oxobutanoic acid, 2-(1,1-dioxidotetrahydro-3-thienyl)-, ethyl ester; Ethyl 2-(sulfolane-3-yl)acetoacetate; 2-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-oxobutanoic acid ethyl ester; Ethyl 3-oxo-2-(1,1-dioxotetrahydrothiophen-3-yl)butanoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(1,1-Dioxidotetrahydrothien-3-Yl)-3-Oxobutanoate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.